About Trickular Tablets
[Overview of this drug]
Brand name: Trickular 21 tablets / 28 tablets
Generic name (active ingredient) Levonorgestrel and ethinyl estradiol
Manufacturing and sales company: Bayer Yakuhin, Ltd.
[Appearance of this medicine]
21 lock type
28 tablets type
What is the purpose of this medicine? ]
・ It is prescribed for the purpose of contraception.
・ It has been reported that the failure rate in general use including forgetting to take the oral contraceptive for one year is 9%.
・ Oral contraceptives do not prevent HIV infection (AIDS) and other sexually transmitted diseases.
[What is the effect of this medicine? ]
-This drug has an ovulation-suppressing effect as its main effect, and exerts a contraceptive effect by inhibiting implantation due to changes in the endometrium and inhibiting sperm passage due to changes in cervical mucus.
・ It has an ovulation inhibitory effect, an implantation inhibitory effect due to changes in the properties of the endometrium, and a sperm passage inhibitory effect due to changes in cervical mucus.
[What is the dosage and administration of this drug? ]
● Trickular Tablets 21
Administer 1 tablet daily for 21 consecutive days (starting with reddish brown sugar-coated tablets) at a fixed time every day, and take a 7-day rest period.
The above 28 days is regarded as one administration cycle, and tablets of the next cycle are administered from the 29th day regardless of whether the bleeding has ended or continued, and the same procedure is repeated thereafter.
● Trickular Tablets 28
Administer one tablet daily at a fixed time for 28 consecutive days (starting with a reddish-brown sugar-coated tablet).
The above 28 days is regarded as one administration cycle, and tablets of the next cycle are administered from the 29th day regardless of whether the bleeding has ended or continued, and the same procedure is repeated thereafter.
When do you take this medicine? ]
・ Please take at a certain time every day. Start date: If you are taking an oral contraceptive for the first time, start taking it on the first day of your menstrual period. If the start date is delayed from the first day of menstruation, use other contraceptive methods for the first week of taking the drug.
・ When switching from other oral contraceptives to this drug When switching from
21-tablet type oral contraceptives: Take all the drugs that were taken before, and after a 7-day rest period, continue to take this drug. Please start. If you are late in taking the drug, you may be pregnant.
When switching from the 28-tablet type oral contraceptive: Take all the medicines you were taking before, and then start taking this medicine. If you are late in taking the drug, you may be pregnant.
[What
to do if you miss a dose] If you miss a dose (excluding the 28-tablet white sugar-coated tablets (large)), if you notice it by the next day, immediately take the missed tablet and take the tablet for that day as well. Take as usual.
If you miss a dose for more than 2 consecutive days, you should stop taking it, wait for the next menstruation, and resume administration. If you miss a dose, you are more likely to become pregnant, so use another contraceptive method for that cycle.
What are the side effects of this drug? ]
-Serious side effects: thrombosis (limbs, lungs, heart, brain, retina, etc.) (incidence unknown) Sudden pain / swelling of lower limbs, sudden shortness of breath, chest pain, severe headache, weakness / paralysis of limbs, dysarthria, If symptoms such as acute visual impairment appear, immediately discontinue administration and seek appropriate treatment.
・ Other side effects: hypersensitivity → rash. Visual acuity disorder due to urticaria, eye → retinal blood flow disorder. Liver → liver dysfunction, jaundice, electrolyte metabolism, edema, weight gain. Uterus → lower abdominal pain, increased vaginal bleeding, candida vaginitis, genital bleeding. Breast → Breast tightness, breast pain. Cardiovascular → palpitation, increased blood pressure. Digestive system → nausea, vomiting, diarrhea, abdominal pain, constipation, loss of appetite, increased appetite, mouth ulcer, dry mouth. Psycho-nervous system → headache dizziness, migraine, nervousness hypersensitivity drowsiness, depression. Skin: Acne Brown spots, eczema. Others → Low back pain, fatigue / fatigue, stiff shoulders, shortness of breath, decreased libido, nose bleeding, numbness, increased total cholesterol, increased triglyceride
[People who fall under the following cannot use this medicine. ]
-Patients with a predisposition to hypertension to the ingredients of this drug-
Patients with abnormal organ bleeding whose diagnosis has not been confirmed-Patients
with thrombotic venitis, pulmonary embolism, cerebral vascular disorders, coronary artery disease or a history thereof
・ Smokers aged 35 years or older with 15 or more cigarettes a day
・ Patients with migraine with precursors (flash dark spots, star-shaped flashes, etc.)
・ Patients with pulmonary hypertension or valvular heart disease with atrial fibrillation, subacute Patients with valvular heart disease with a history of bacterial endocarditis,
diabetic patients with vascular lesions (diabetic nephropathy, diabetic retinopathy, etc.)
, women with thrombotic predisposition,
patients with antiphospholipid antibody syndrome
・ Patients within 4 weeks before surgery, within 2 weeks after surgery, within 4 weeks after childbirth and long-term rest ・ Patients
with severe liver damage ・ Patients
with liver tumor ・
Patients with abnormal lipid metabolism
・ Hypertension Patients (excluding patients with mild hypertension) -Patients
with ear sclerosis-Patients with
a history of jaundice, persistent pruritus or pregnancy herpes during pregnancy
-Pregnant women or women who may be pregnant
-Breasting Women
・ Women who may not have completed bone growth
[Important basic precautions] Taking
this drug may cause thrombosis regardless of risk factors such as age, smoking, obesity, and family history. If any of the following symptoms occur, immediately Stop taking the drug and seek appropriate treatment.
・ Main symptoms of thrombosis requiring emergency response: Sudden pain / swelling of lower limbs, sudden shortness of breath, chest pain, severe headache, weakness / paralysis of limbs, dysarthria, acute visual impairment, etc.
・ Symptoms of suspected thrombosis: Lower limb pain / swelling / numbness / redness / heat sensation, headache, nausea / vomiting, etc.
[Notes on patients with specific backgrounds]
Please be sure to tell your doctor if any of the following applies.
・ Patients with complications ・ History ・
Women over 40 years old ・
Patients with uterine myoma ・
Women with a history of breast
cancer ・ Women with a family history of breast cancer or nodules in the breast
・ Smokers
・ Obese women
・Women with a family history of thrombosis -Patients with
unpredictable migraine-Patients
with cardiovalvular disease-Patients
with mild hypertension (including history of hypertension during pregnancy) -Patients
with reduced glucose tolerance-
Patients with porphyrinosis,
epilepsy
, patients with tetani, patients
with renal dysfunction
, patients with renal disease or a history of it, patients
with hepatic dysfunction
, those who may be pregnant, pregnant women
, lactating women
[Others]
・ Please take the medicine in the PTP package from the PTP sheet and take it. Hard sharp corners may pierce the esophageal mucosa and cause perforation, leading to serious complications such as mediastinitis.
・ Keep out of reach of children